cytofocus
ask
submit
botany
pathology
histology
microbiology
zoology
diatoms
Archive
a microscopy blog
cellularemergence:

Under the microscope: more diatoms in various shapes and sizes :)

cellularemergence:

Under the microscope: more diatoms in various shapes and sizes :)

cellularemergence:

Art Deco Diatoms by Wim van Egmond. (diatoms are microscopic aquatic organisms)

cellularemergence:

Art Deco Diatoms by Wim van Egmond. (diatoms are microscopic aquatic organisms)


turns out your brain is lined by gumballs…er…ependymal cells
ependyma is one of the four types of neuroglia in the central nervous system, constituting an epithelium-like layer that lines the ventricles and central canal of the spinal cord
it also produces cerebrospinal fluid (CSF)
note that in the fetus (here), ependymal cells are not ciliated
colored SEM, 1000x
credit: Steve Schmeissner

turns out your brain is lined by gumballs…er…ependymal cells

ependyma is one of the four types of neuroglia in the central nervous system, constituting an epithelium-like layer that lines the ventricles and central canal of the spinal cord

it also produces cerebrospinal fluid (CSF)

note that in the fetus (here), ependymal cells are not ciliated

colored SEM, 1000x

credit: Steve Schmeissner


Lateral view of a late-stage mouse embryo, stained for bone (Alizarin Red) and cartilage (Alcian Blue).

Lateral view of a late-stage mouse embryo, stained for bone (Alizarin Red) and cartilage (Alcian Blue).

Selections from Slate’s fantastic gallery of Incredible Photos of Tiny Animal Partsa collection of some of best animal entries to the Nikon Small World competition last year.


Neuralstem Cell Transplant for Post-Stroke Symptom
Neuralstem Inc has a peer-reviewed paper published talking about the improvements of rat brain after ischemic-stroke with the use of NSI566 neural stemcells. 

Neuralstem is currently conducting a Phase II NSI-566 clinical trial in amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease) in three U.S. sites, as well as a Phase I/II to treat post-stroke motor deficit in China, through its wholly-owned subsidiary, Neuralstem China. The company also has been approved by the FDA to commence a trial with the same cells to treat chronic spinal cord injury.

This is only one of the great research projects going on in the biotech hub Rockville Maryland.. where I will be for the next year!I can’t wait.

Neuralstem Cell Transplant for Post-Stroke Symptom

Neuralstem Inc has a peer-reviewed paper published talking about the improvements of rat brain after ischemic-stroke with the use of NSI566 neural stemcells. 

Neuralstem is currently conducting a Phase II NSI-566 clinical trial in amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease) in three U.S. sites, as well as a Phase I/II to treat post-stroke motor deficit in China, through its wholly-owned subsidiary, Neuralstem China. The company also has been approved by the FDA to commence a trial with the same cells to treat chronic spinal cord injury.

This is only one of the great research projects going on in the biotech hub Rockville Maryland.. where I will be for the next year!

I can’t wait.


Keratinized and Immortalized
Image SK2802 (HaCaT Culture Cells)  Immunofluorescence light micrograph of HaCaT daughter cells that have resulted from one cell dividing into two (mitosis). The nuclei, which contain the cell’s genetic information, are red. The yellow strands are microtubules, which are involved in cell division. HaCaT cells are human skin cells (keratinocytes) that have been transformed (mutated) to be immortal. They have unlimited growth potential, but unlike other immortal cell lines they are not tumorigenic, meaning non-tumor forming. They grow in an orderly fashion and retain all the structural and functional features of human skin. HaCaT cells are grown in the laboratory and are used in research, including wound healing research. Magnification: x980 when printed 10cm wide.
© Dr. Torsten Wittmann / Science Source

Keratinized and Immortalized

Image SK2802 (HaCaT Culture Cells)  Immunofluorescence light micrograph of HaCaT daughter cells that have resulted from one cell dividing into two (mitosis). The nuclei, which contain the cell’s genetic information, are red. The yellow strands are microtubules, which are involved in cell division. HaCaT cells are human skin cells (keratinocytes) that have been transformed (mutated) to be immortal. They have unlimited growth potential, but unlike other immortal cell lines they are not tumorigenic, meaning non-tumor forming. They grow in an orderly fashion and retain all the structural and functional features of human skin. HaCaT cells are grown in the laboratory and are used in research, including wound healing research. Magnification: x980 when printed 10cm wide.

© Dr. Torsten Wittmann / Science Source


Sunflower pollen | ©Louisa Howard-FEI Company
Pollen of the Common Sunflower,  Helianthus annuus (Asterales - Asteraceae).
Magnification: 1410x

Sunflower pollen | ©Louisa Howard-FEI Company

Pollen of the Common Sunflower,  Helianthus annuus (Asterales - Asteraceae).

Magnification: 1410x


Cell division is an intricate chemical dance that is part individual, part community-driven.
From the TED-Ed Lesson How do cancer cells behave differently from healthy ones? - George Zaidan

Cell division is an intricate chemical dance that is part individual, part community-driven.

From the TED-Ed Lesson How do cancer cells behave differently from healthy ones? - George Zaidan


Researchers Show How Lost Sleep Leads to Lost Neurons
First report in preclincal study showing extended wakefulness can result in neuronal injury.
Most people appreciate that not getting enough sleep impairs cognitive performance. For the chronically sleep-deprived such as shift workers, students, or truckers, a common strategy is simply to catch up on missed slumber on the weekends. According to common wisdom, catch up sleep repays one’s “sleep debt,” with no lasting effects. But a new Penn Medicine study shows disturbing evidence that chronic sleep loss may be more serious than previously thought and may even lead to irreversible physical damage to and loss of brain cells. The research is published today in the Journal of Neuroscience.
Continue Reading

Researchers Show How Lost Sleep Leads to Lost Neurons

First report in preclincal study showing extended wakefulness can result in neuronal injury.

Most people appreciate that not getting enough sleep impairs cognitive performance. For the chronically sleep-deprived such as shift workers, students, or truckers, a common strategy is simply to catch up on missed slumber on the weekends. According to common wisdom, catch up sleep repays one’s “sleep debt,” with no lasting effects. But a new Penn Medicine study shows disturbing evidence that chronic sleep loss may be more serious than previously thought and may even lead to irreversible physical damage to and loss of brain cells. The research is published today in the Journal of Neuroscience.

Continue Reading